Test Your Knowledge - Free MCQ PRACTICE
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A fresh set of 20 random questions is generated every time you open this page and every time you refresh it.
For each of the following multiple choice questions, choose the most appropriate answer :

1. This drug is contraindicated in patients with bronchial asthma:
A. Propranolol
B. Clonidine
C. Enalapril
D. Nifedipine

2. Indication for etidronate administration is:
A. Malabsorption of vitamin D from intestine
B. Paget's disease
C. Vitamin D deficiency in a diet
D. Hypercalciuria

3. What does “affinity” mean?
A. A measure of how tightly a drug binds to plasma proteins
B. A measure of how tightly a drug binds to a receptor
C. A measure of inhibiting potency of a drug
D. A measure of bioavailability of a drug

4. Given a graph of plasma drug concentration versus time, what part of the graph would be used to calculate bioavailability for a PO (oral) drug administration?
A. Maximum concentration
B. Steady concentration
C. Derivative of the curve (slope)
D. Integral of the curve (area underneath)

5. Select the antiseizure drug with an analgesic component of effect:
A. Carbamazepine
B. Ethosuximide
C. Phenytoin
D. Clonazepam

6. Repeated administration of acetophenetidin has adverse effect upon :
A. A . Kidney
B. Liver
C. Eye sight
D. Hearing

7. Currently used second-generation sulfonylureas include the following, EXCEPT:
A. Glyburide (Glibenclamide)
B. Glipizide (Glydiazinamide)
C. Glimepiride (Amaril)
D. Tolbutamide (Orinase)

8. Tick praziquantel mechanism of action:
A. Blocking acetylcholine transmission at the myoneural junction and paralysis of helminthes
B. Inhibiting microtubule synthesis in helminthes and irreversible impairment of glucose uptake
C. Increasing cell membrane permeability for calcium, resulting in paralysis, dislodgement and death of helminthes
D. Inhibiting oxidative phosphorylation in some species of helminthes

9. Which of the following direct-acting cholinomimetics is mainly muscarinic in action?
A. Bethanechol
B. Carbachol
C. Acetylcholine
D. None of the above

10. Hypnotic drugs should:
A. Reduce anxiety and exert a calming effect
B. Induce absence of sensation
C. Produce drowsiness, encourage the onset and maintenance of sleep
D. Prevent mood swings in patients with bipolar affective disorders

11. Tick the antimalarial drug belonging to 8-aminoquinoline derivatives:
A. Doxycycline
B. Quinidine
C. Primaquine
D. Chloroquine

12. Prescribed: 1000 mL of IV fluid q12h. Available: 1000 mL of IV fluid and microdrip tubing. How many gtts per minute will you regulate the IV?
A. 83 gtt/min
B. 83.3 gtt/min
C. 8.33 gtt/min
D. 0.833 gtt/min

13. Mechanism of aspirin action is:
A. Converts inactive plasminogen into active plasmin
B. Inhibits COX and thus thromboxane synthesis
C. Enhances the interaction between antitrombin III and both thrombin and the factors involved in the intrinsic clotting cascade
D. Inhibits the glycoprotein IIb/IIIa complex

14. Which of the following is NOT a site of loss (where drug is not used)?
A. Fat
B. GI tract
C. Muscle
D. Site lacking receptors

15. Indicate the intravenous anesthetic, which produces dissociative anesthesia:
A. Midazolam
B. Ketamine
C. Fentanyl
D. Thiopental

16. The uptake of glucose by calls is an example of :
A. Simple diffusion
B. Filtration
C. Active transport
D. Faciliated diffusion

17. Mechanism of Izoniazid action is:
A. Inhibition of protein synthesis
B. Inhibition of mycolic acids synthesis
C. Inhibition of RNA synthesis
D. Inhibition of ADP synthesis

18. Aminocapronic acid is a drug of choice for treatment of:
A. Acute myocardial infarction
B. Bleeding from fibrinolytic therapy
C. Heart failure
D. Multiple pulmonary emboli

19. Tick the positive inotropic drug of non-glycoside structure:
A. Digitoxin
B. Digoxin
C. Dobutamine
D. Strophanthin

20. Management of alcohol withdrawal syndrome contains:
A. Restoration of potassium, magnesium and phosphate balance
B. Thiamine therapy
C. Substituting a long-acting sedative-hypnotic drug for alcohol
D. All of these

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