A fresh set of 20 random questions is generated every time you open this page and every time you refresh it.For each of the following multiple choice questions, choose the most appropriate answer :
1. All of the following are undesirable effects of aspirin EXCEPT:
A. Gastritis with focal erosions
B. Tolerance and physical addiction
C. Bleeding due to a decrease of platelet aggregation
D. Reversible renal insufficiency
2. Indicate the neuromuscular blocker, whose breakdown product readily crosses the blood-brain barrier and may cause seizures:
A. Pancuronium
B. Succinylcholine
C. Tubocurarine
D. Atracurium
3. Subtype-selective alfa1 receptor antagonists such as tamsulosin, terazosin, alfusosin are efficacious in:
A. Hyperthyroidism
B. Cardiac arrhythmias
C. Benign prostatic hyperplasia (BPH)
D. Asthma
4. Nicotinic ACh receptors (ligand-gated) involve the movement of what ion across the membrane?
A. K+
B. Ca++
C. Cl-
D. Na+
5. Which of the following statements is correct for levodopa?
A. Tolerance to both beneficial and adverse effects develops gradually
B. Levodopa is most effective in the first 2-5 years of treatment
C. After 5 years of therapy, patients have dose-related dyskinesias, inadequate response or toxicity
D. All of these
6. Tick the unwanted effects of indinavir:
A. Hypotension, vomiting, dizziness
B. Nephrolithiasis, nausea, hepatotoxicity
C. Peripheral neuropathy, pancreatitis, hyperuricemia
D. Anemia, neutropenia, nausea
7. Tick the drug which belongs to nucleoside reverse transcriptase inhibitors:
A. Didanosine
B. Gancyclovir
C. Nevirapine
D. Vidarabine
8. Systemic clearance (CLs) is related with:
A. Only the concentration of substances in plasma
B. Only the elimination rate constant
C. Volume of distribution, half life and elimination rate constant
D. Bioavailability and half life
9. Indicate the drug, which has greater potency of the local anesthetic action:
A. Lidocaine
B. Bupivacaine
C. Procaine
D. Mepivacaine
10. Epinephrine decreases intracellular camp levels by acting on:
A. ?1 receptor
B. ?2 receptor
C. beta1 receptor
D. beta2 receptor
11. Tick the drug used for amoebiasis treatment:
A. Nitrofurantoin
B. Iodoquinol
C. Pyrazinamide
D. Mefloquine
12. Which of the following features do MAO inhibitors and tricyclic antidepressants have in common?
A. Act postsynaptically to produce their effect
B. Can precipitate hypotensive crises if certain foods are ingested
C. Increase levels of biogenic amines
D. Are useful for the manic phase of bipolar disorder
13. Indicate the inhaled anesthetic, which should be avoided in patients with a history of seizure disorders:
A. Enflurane
B. Nitrous oxide
C. Sevoflurane
D. Desflurane
14. Aspirin readily donates a proton in aqueous solutions and pyrimethamine readily accepts a proton in aqueous solution. Thus, aspirin is a(b) ____ and pyrimethamine is a(n) ____.
A. Acid; Base
B. Base; Acid
C. Acid; Acid
D. Base; Base
15. Contact dermatitis is caused by
A. pollen.
B. sunlight.
C. plants.
D. None of these
16. Which of the following drugs is an nonselective beta receptor antagonist?
A. Metoprolol
B. Atenolol
C. Propranolol
D. Acebutolol
17. Which of the following is most useful in determining the rate of elimination of a drug, in general?
A. Drug concentration in urine (renal elimination)
B. Drug concentration in stool (bilary elimination)
C. Drug concentration in blood
D. Drug concentration in brain
18. The following statements concerning mechanism of calcium channel blockers’ action are true, EXCEPT:
A. Therapeutically active agents in this group are capable of releasing nitric oxide (NO) in vascular smooth muscle target tissues
B. Calcium channel blockers bind to L-type calcium channel sites
C. Calcium channel blockers useful in angina decrease myocardial oxygen requirement (by decreasing the determinations of oxygen deman and increase myocardial oxygen delivery (by reversing coronary arterial spasm)
D. Calcium channel blockers decrease transmembrane calcium current associated in smooth muscle with long-lasting relaxation and in a cardiac muscle with a reduction in contractility
19. Weak acids are excreted faster in ____ urine and weak bases are excreted faster in ____ urine.
A. Acidic; Alkaline
B. Alkaline; Acidic
C. Acidic; Neutral
D. Neutral; Alkaline
20. Indicate a cholinomimetic agent, which is related to direct-acting drugs:
A. Edrophonium
B. Physostigmine
C. Carbachol
D. Isoflurophate
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