A fresh set of 20 random questions is generated every time you open this page and every time you refresh it.For each of the following multiple choice questions, choose the most appropriate answer :
1. Indicate an alfa1 adrenoreceptor antagonist, which has great selectivity for alfa1a subtype:
A. Prazosin
B. Tamsulosin
C. Phenoxybenzamine
D. Phentolamine
2. Tick the main approach of peptic ulcer treatment:
A. Neutralization of gastric acid
B. Eradication of Helicobacter pylori
C. Inhibition of gastric acid secretion
D. All the above
3. Which of the following agents is related to hallucinogens?
A. Heroin
B. LSD
C. Cocaine
D. Opium
4. Tick the substances whose mechanisms are based on interaction with ion channels
A. Sodium channel blockers
B. Calcium channel blockers
C. Potassium channels activators
D. All of the above
5. Which category of histamine H1 antagonists is noted for the best antiemetic action?
A. Alkylamines (propylamines); i.e. Brompheniramine
B. Ethanolamines (aminoalkyl ethers); i.e. Doxylamine
C. Piperazines; i.e. Hydroxyzine, Cyclizine
D. Ethylenediamines; i.e. Suprastine
6. The metabolism of griseofulvin is accelerated by :
A. Chlorpromazine
B. Promethazine
C. Phenobarbitone
D. Diazepam
7. Main complications of estrogens’ therapy include the following:
A. Postmenopausal uterine bleeding
B. Breast tenderness
C. Hyperpigmentation
D. All of these
8. Which of the following preparations combines carbidopa and levodopa in a fixed proportion?
A. Selegiline
B. Sinemet
C. Tolkapone
D. Biperiden
9. Which of the following is NOT an action of the body on a drug?
A. Absorption
B. Distribution
C. Metabolism
D. Side effects
10. Mechanism of Amphotericin B action is:
A. Inhibition of cell wall synthesis
B. Inhibition of fungal protein synthesis
C. Inhibition of DNA synthesis
D. Alteration of cell membrane permeability
11. This drug is useful in terminating atrial but not ventricular tachycardias:
A. Flecainide
B. Sotalol
C. Lidocaine
D. Verapamil
12. Which of the following drugs causes bronchodilation without significant cardiac stimulation?
A. Isoprenaline
B. Terbutaline
C. Xylometazoline
D. Methoxamine
13. Which of the following statements concerning beta-adrenoceptor-blocking drugs are true:
A. These agents decrease transmembrane calcium current associated in a smooth muscle with long-lasting relaxation and in a cardiac muscle with a reduction in contractility
B. These agents has a moderate reflex and vascular dilative action caused by the stimulation of sensitive nerve endings
C. Beneficial effects of these agents are related primarily to their hemodynamic effects – decreased heart rate, blood pressure, and contractility – which decrease myocardial oxygen requirements at rest and during exercise
D. e)These agents increase the permeability of K channels, probably ATP-dependent K channels, that results in stabilizing the membrane potential of excitable cells near the resting potential
14. Patients receiving sulphonamides should not receive :
A. Prolonged exposure to direct sunlight,
B. Excess of coal fumes
C. Excess of alcoholic drinks
D. Drugs containing aminoquinolines
15. Which of the following general anesthetics belongs to inhalants?
A. Thiopental
B. Desfluran
C. Ketamine
D. Propofol
16. A patient diagnosed with type 2 diabetes is administered an oral dose of 0.1 mg chloropropamide, an insulin secretagogue and weak acid with a pKa of 5.0. What is the amount of this drug that could be absorbed from the stomach at pH 2.0?
A. 99.9 µg
B. 90 µg
C. 50 µg
D. 0.05 mg
17. Which of the following anxiolitics is a benzodiazepine derivative:
A. Buspirone
B. 1Clordiazepoxide
C. 2Meprobamate
D. 3Chloral hydrate
18. The principle of drug manipulation for excretion of a drug out of the renal tubule can be accomplished by:
A. Acidifying the urinary pH
B. Adjusting the urinary pH to protonate weakly acidic drugs
C. Adjusting the urinary pH to unprotonate weakly basic drugs
D. Adjusting the urinary pH to ionize the drug
19. Target proteins which a drug molecule binds are:
A. Only receptors
B. Only ion channels
C. Only carriers
D. All of the above
20. Which of the following drugs may cause reversible gynecomastia?
A. Omeprazole
B. Pirenzepine
C. Cimetidine
D. Sucralfate
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