A fresh set of 20 random questions is generated every time you open this page and every time you refresh it.For each of the following multiple choice questions, choose the most appropriate answer :
1. Where in a eukaryotic cell, DNA can be found?
A. Nucleus
B. Mitochondrion
C. Vacuole
D. Both (a) and (b)
2. The conformational changes from the T to the R state is initiated by
A. binding of oxygen to the heme
B. movement of the proximal histidine towards the heme
C. movement of the F-helix, which contains the proximal His
D. reorganization of protein-protein contacts between the individual subunits
3. Which of the following is the best described glucogenic amino acid?
A. Lysine
B. Tryptophan
C. Valine
D. None of these
4. How many ATP equivalents per mole of glucose input are required for gluconeogenesis?
A. 2
B. 6
C. 8
D. 4
5. In Counter immunoelectrophoresis
A. electrophoresis will drive the antibody and antigen parallel to each other
B. electrophoresis will drive the antibody and antigen toward each other
C. the antibody will migrate towards anode
D. the antibody will migrate towards cathode
6. Which of the following is an allosteric activator of hepatic glutamate dehydrogenase?
A. ATP
B. ADP
C. GTP
D. NADH
7. Which of the following immune cells would have an especially low count in a patient with advanced AIDS?
A. Killer T lymphocytes
B. Helper T lymphocyte
C. B lymphocytes
D. None of these
8. Which of the following amino acids is considered as both ketogenic and glucogenic?
A. Valine
B. Tryptophan
C. Lysine
D. None of these
9. Isoschizomers recognize
A. same recognition sequence but different recognition site
B. same recognition site and recognition sequence
C. same recognition site and different recognition sequence
D. different recognition site and different recognition sequence
10. The chromosomal DNA complexes with
A. three types of histone as H1, H2A and H4
B. five types of histone as H1, H2A, H2B, H3 and H4
C. four types of histone as H1, H2A, H3 and H4
D. two types of histone as H1 and H4
11. A mutation in the tip binding site of the repressor would result in
A. constitutive trp operon expression
B. inducible trp operon expression
C. no operon expression
D. none of the above
12. Ion exchange chromatography is based on the
A. electrostatic attraction
B. electrical mobility of ionic species
C. adsorption chromatography
D. partition chromatography
13. What is the relationship between wavelength and wave number?
A. Wavenumber = 1 / wavelength in centimeters
B. Wavenumber - wavelength in nanometers = 1
C. Wavelength in nanometers x wavenumber = 1
D. None of the above
14. SH2 domains specifically bind to
A. phosphorylated serine residues
B. phosphorylated tyrosine residues
C. GDP
D. Ca2+
15. The symptoms of retinol excess are
A. bone fragility
B. nausea
C. weakness
D. all of these
16. Which of these restriction enzymes produce blunt ends?
A. SaII
B. EcoRV
C. XhoI
D. HindIII
17. What is the specificity of the Clostripain protease?
A. It cleave after Arg residues
B. It cleave after His residues
C. It cleave after Lys residues
D. None of the above
18. At the midpoint of a temperature transition curve,
A. half of the protein is denatured
B. Keq = 1.0 and ?G = 0
C. [Native] = [Unfolded]
D. All of these
19. Which of the following is the substrate for rate-limiting enzyme of polyamine biosynthesis?
A. Histidine
B. Cadaverine
C. Ornithine
D. Anandamide
20. When protein binds two ligands in a non-cooperative manner, then the x-intercept of the Scatchard Plot is
A. 1
B. 2
C. not defined
D. none of the above
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