A fresh set of 20 random questions is generated every time you open this page and every time you refresh it.For each of the following multiple choice questions, choose the most appropriate answer :
1. Cells filled with globules of myelin fat (foamy cells) are especially abundant in lesions of :
A. Tuberculosis
B. Syphilis
C. Leprosy
D. Actinomycosis
2. Ductus arteriosus gets obliterated during intra-uterine life during about :
A. Third week
B. Ninth week
C. Fifteenth week
D. Twenty-first week
3. In the process of thrombosis, the first occurence is :
A. Agglutination of platelets
B. Fusion of platelets
C. Deposition of platelets
D. Diffusion of thromboplastin
4. Regarding complement
A. C5a is an important opsonising molecule.
B. C3b has chemotactic function.
C. it cannot cause cytolysis of bacteria in the absence of immune complexes.
D. C3a may cause mast cell degranulation
5. Down's syndrome (Mongolism) is due to trisomy of chromosome number :
A. 15
B. 17
C. 19
D. 21
6. Concerning vascular leakage with acute inflammation
A. endothelial cell contraction preferentially occurs in arterioles 20-60 µm in diameter.
B. tumour necrosis factor (TNF) affects leakage by direct endothelial cell necrosis.
C. immediate sustained response is due to widening of intercellular gaps.
D. chemically mediated endothelial contraction is usually reversible
7. Gangrene is the death of a part accompanied by :
A. Suppuration
B. Putrefaction
C. Calcification
D. Fibrosis
8. In Barrett's Esophagus
A. Intestinal Metaplasia
B. Intestinal Dysplasia
C. Gastric Dysplasia
D. Squamous Metaplasia
9. Breast cancer is predisposed by :
A. Increase in estrogen
B. Decrease in estrogen
C. Increase in androgen
D. Decrease in androgen
10. The pigment haematoidin is most identical with :
A. Porphyrin
B. Bilirubin
C. Haemosiderin
D. Haemozoin
11. An example of chronic fibrinoid inflammation is :
A. Chronic cervicitis
B. Chronic gastritis
C. Chronic cholecystitis
D. None of these
12. Chromophobe variant of renal cell carcinoma is associated with
A. VHL gene mutations
B. Trisomy of 7 and 17 (+7, +17)
C. 3 p deletions (3p-)
D. Monosomy of 1 and Y (-1, -Y)
13. In haemophilia bleeding is due to the deficiency of :
A. Factor VI
B. Factor VII
C. Factor VIII
D. Factor IX
14. The causes of vascular changes in inflammation are :
A. Nervous factors (axon reflex)
B. Chemical-'H' like substance and leucotaxin
C. Anoxia
D. All of these
15. Which of the following is the most characteristic ultrastructural feature of paraganglioma on electron microscopy?
A. Shrunken mitochondria
B. Large Golgi apparatus
C. Frequent mitoses
D. Dense core neuroendocrine granules
16. Syphilitic gumma occurs in :
A. Early primary stage
B. Late primary stage
C. Secondary stage
D. Tirtiary stage
17. Plasma cell contains :
A. Golgi body
B. Inclusion bodies
C. Auer body
D. Russel bodies
18. In Lewis Triple Response, redness when skin is scratched with a pointed object is seen due to
A. Axon Reflex causing Vasoconstriction
B. Histamine Release due to local injury to mast cells by pointing device-
C. Free Nerve Endings
D. Endothelial Damage leading to increase in permeability
19. Under the conditions of stress, the differential leucocyte count shows :
A. Decrease in polymorphs
B. Increase in polymorphs
C. Decrease in lymphocytes
D. Decrease in eosinophils
20. Which is not seen with apoptosis
A. Cell shrinkage
B. Nuclear condensation
C. Inlammation
D. All of the above
Dr K Chaudhry 5 Alpha Inmternational City, Fatehabad 125050 M: 9810570740, 9810571993facebook.com/doctorkc