A fresh set of 20 random questions is generated every time you open this page and every time you refresh it.For each of the following multiple choice questions, choose the most appropriate answer :
1. The most likely interval between infection and appearance of secondary lesions in syphilis is :
A. 2-3 hours
B. 2-3 days
C. 2-3 weeks
D. 2-3 months
2. From inside to the outside, the layers of the arterial wall compose of:
A. endothelium, muscularis mucosa, external elastic lamina, adventitia
B. tunica interna, tunica media, internal elastic lamina, adventitia
C. endothelium, internal elastic lamina, muscle layer, external elastic lamina, adventitia
D. endothelium, muscle layer, internal elastic lamina, adventitia, external elastic lamina
3. A true capsule Occurs in :
A. Rhabdomyoma
B. Ewing's tumour
C. Leiomyoma of uterus
D. Benign haemangioma
4. Massive liver cell necrosis may be caused by protein deficiency superimposed on depletion of :
A. Vitamin A
B. Vitamin B
C. Vitamin D
D. Vitamin E
5. Characteristic pathological finding in carcinoid heart disease is:
A. Fibrous endocardial thickening of right ventricle, tricuspid valve & pulmonary valve
B. Endometrial thickening of tricuspid valve with severe tricuspid stenosis
C. Collagen rich, elastic deposits in endocardium of right ventricle and pulmonary valve
D. Calcification of tricuspid and pulmonary valve
6. The characteristic feature of apoptosis on light microscopy is
A. cellular swelling
B. nuclear compaction
C. intact cell membrane
D. Cytoplasmic eosinophlia
7. Calcification of media is most related to :
A. Atherosclerosis
B. Monckeberg's sclerosis
C. Diffuse arteriolar sclerosis
D. Thrombotic sclerosis
8. Males are more commonly affected than females in:
A. Autosomal Dominant
B. Autosomal Recessive
C. X-linked dominant
D. X-linked recessive
9. Fanconi syndrome usually becomes apparent during :
A. Intrauterine life
B. Childhood
C. Puberty
D. Middle age
10. With regard to eicosanoids
A. main action of LTB4 is to increase permeability.
B. PGE2 causes intense vasoconstriction.
C. permeability increase caused by LTD4 restricted to venules.
D. LTC4, LTD4, LTE4, are important vasodilators
11. Which of the following is NOT a complication of long term diabetes mellitus?
A. accelerated arteriosclerosis.
B. diffuse glomerulosclerosis.
C. increased synthesis of type IV collagen.
D. increased myoinositol in nerves
12. Sero-fibrinous inflammation of the pericardium is most likely to be :
A. Acute idiopathic pericarditis
B. Pneumococcal pericarditis
C. Rheumatic pericarditis
D. Tuberculous pericarditis
13. Ductus arteriosus gets obliterated during intra-uterine life during about :
A. Third week
B. Ninth week
C. Fifteenth week
D. Twenty-first week
14. Rheumatic carditis affects :
A. Pericardium
B. Myocardium
C. Endocardium
D. All of these
15. Vitamin C deficiency results in
A. a decreased number of collagen fibres.
B. an increased elastin:collagen ratio.
C. formation of defective collagen fibres.
D. detachment of ribosomes in fibroblasts
16. Dystrophic calcification :
A. occurs in dead or dying tissues
B. occurs in hypertrophied tissue
C. occurs in hypercalcaemia
D. occurs in hypervitaminosis D
17. A characteristic of myeloblasts is :
A. Golgi bodies
B. Inclusion bodies
C. Russel bodies
D. Auer bodies
18. Irreversible cellular injury is characterised by all, EXCEPT
A. progressive loss of phospholipids.
B. decreased activity of Na+ / K+ ATPase causing cellular swelling.
C. damage to the cellular cytoskeleton.
D. the presence of reactive O2 species
19. What is used for diagnosis of fragment of chromosomes
A. FISH
B. CGH
C. PCR
D. RFLP
20. Embryonic haemoglobin is composed up of :
A. Alpha and beta
B. Epsilon and gamma
C. Gamma and beta
D. Zeta and epsilon
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