Test Your Knowledge - Free MCQ PRACTICE
PHARMACOLOGY
by Dr K Chaudhry
MACHINIST
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A fresh set of 20 random questions is generated every time you open this page and every time you refresh it.
For each of the following multiple choice questions, choose the most appropriate answer :

1. Tick the unwanted effects of Metronidazole:
A. Nausea, vomiting, diarrhea, stomatitis
B. Hypertension
C. Disturbances of peripheral blood circulation
D. All of these

2. This drug is used in treating supraventricular tachycardias:
A. Digoxin
B. Dobutamine
C. Amrinone
D. Dopamine

3. A target concentration of 7.5 mg/L of theophylline is required for a 60 kg patient. What is the loading dose, given the following: Vd = 0.5 L/kg, Cl = 0.04 L/kg/hr, t(1/2) = 9.3 hr?
A. 0.5 L/kg * 60 kg * 7.5 mg/L = 225 mg/h, infusion
B. 0.5 L/kg * 60 kg * 7.5 mg/L = 225 mg, bolus
C. 0.04 L/kg/hr * 60 kg * 7.5 mg/L = 18 mg/h, infusion
D. 0.04 L/kg/hr * 60 kg * 7.5 mg/L = 18 mg, bolus

4. Characteristics of epinephrine include all of the following EXCEPT:
A. It is synthesized into the adrenal medulla
B. It is synthesized into the nerve ending
C. It is transported in the blood to target tissues
D. It directly interacts with and activates adrenoreceptors

5. Amanita muscaria (fly Amanita) is a fungal muscarinic agonist, which is most often associated with which side effect?
A. Bradycardia
B. Euphoria
C. Sedation
D. Hallucinations

6. Which of the following adrenergic receptor activation mechanisms is involved with MAO inhibitors?
A. Direct binding to the receptor
B. Promoting release of norepinephrine
C. Inhibiting reuptake of norepinephrine
D. Inhibiting inactivation of norepinephrine

7. Alcohol may cause disuliftram-like reaction when administered along with :
A. Diiodohydroxyquinoline
B. Chloroquine
C. Metronidazole
D. Phanquone

8. All of the following effects of ACE inhibitors may be useful in treating heart failure EXCEPT:
A. They decrease afterload
B. They increase circulating catecholamine levels
C. They reduce reactive myocardial hypertrophy
D. They increase myocardial beta-1 adrenergic receptor density

9. What type(s) of second messenger(s) interact with adenylyl cyclase?
A. ?1
B. ?2
C. ? & ?1
D. ? & ?2

10. Which drugs may be used as antianxiety agents?
A. BETA-blocking drugs
B. Clonidine - a partial agonist of alfa2 receptors
C. Tricyclic antidepressants
D. All of these

11. Which of the following ?-blockers is used for decreasing aqueous humor secretions from the ciliary body?
A. Propranolol
B. Nadolol
C. Carvedilol
D. Timolol

12. Flumazenil is used to:
A. Reverse the CNS depressant effects of hypnotic benzodiazepines overdose
B. Hasten recovery following use of hypnotic benzodiazepines in anesthetic and diagnostic procedure
C. Reverse benzodiazepine-induced respiratory depression
D. All of these

13. General contraindications for anticancer drugs are:
A. Depression of bone marrow
B. Acute infections
C. Severe hepatic and/or renal insufficiency
D. All of these

14. Contraindications to the use of antimuscarinic drugs are all of the following except:
A. Glaucoma
B. Myasthenia
C. Bronchial asthma
D. Paralytic ileus and atony of the urinary bladder

15. Tick the second messenger of G-protein-coupled (metabotropic) receptor:
A. Adenylyl cyclase
B. Sodium ions
C. Phospholipase C
D. cAMP

16. The mechanism of haloperidol antipsychotic action is:
A. Blocking D2 receptors
B. Central alpha-adrenergic blocking
C. Inhibition of norepinephrine uptake mechanisms
D. All of these

17. Compliance is
A. the ability of the lungs to be contracted.
B. the ability of the lungs to be distended.
C. the ability of the lungs to exchange gases.
D. None of these

18. Hyperalimentation is
A. parenteral nutrition.
B. enternal nutrition.
C. a high saline concentration for parenteral nutrition therapy.
D. None of these

19. Which of the following fibers is the first to be blocked?
A. Type A alpha fibers
B. B and C fibers
C. Type A beta fibers
D. Type A gamma fibers

20. Indicate the skeletal muscle relaxant, which is a depolarizing agent:
A. Vencuronium
B. Scopolamine
C. Succinylcholine
D. Hexamethonium

Dr K Chaudhry 5 Alpha Inmternational City, Fatehabad 125050 M: 9810570740, 9810571993facebook.com/doctorkc