Test Your Knowledge - Free MCQ PRACTICE
PHARMACOLOGY
by Dr K Chaudhry
MACHINIST
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A fresh set of 20 random questions is generated every time you open this page and every time you refresh it.
For each of the following multiple choice questions, choose the most appropriate answer :

1. Indicate the pure opioid antagonist, which has a half-life of 10 hours:
A. Naloxone
B. Naltrexone
C. Tramadol
D. Pentazocine

2. Which one of the following non-narcotic agents inhibits mainly cyclooxygenase (COX) in CNS?
A. Paracetamol
B. Ketorolac
C. Acetylsalicylic acid
D. Ibuprofen

3. Tick the drug, inhibiting viral DNA synthesis:
A. Interferon
B. Saquinavir
C. Amantadine
D. Acyclovir

4. This drug is a Class II antiarrhythmic drug:
A. Flecainide
B. Propranolol
C. Lidocaine
D. Verapamil

5. Contraindications to the use of antimuscarinic drugs are all of the following except:
A. Glaucoma
B. Myasthenia
C. Bronchial asthma
D. Paralytic ileus and atony of the urinary bladder

6. Tick the unwanted effects of fluoroquinolones:
A. Hallucinations
B. Headache, dizziness, insomnia
C. Hypertension
D. Immunetoxicity

7. Flumazenil is used to:
A. Reverse the CNS depressant effects of hypnotic benzodiazepines overdose
B. Hasten recovery following use of hypnotic benzodiazepines in anesthetic and diagnostic procedure
C. Reverse benzodiazepine-induced respiratory depression
D. All of these

8. Which of the following is NOT true regarding the parasympathetic nervous system?
A. Involves rest and digestion functions
B. Has nicotinic receptors on cell bodies of all postganglionic neurons
C. Target organs have muscarinic receptors for ACh
D. Innervation of vascular smooth muscle

9. Characteristics of reserpine include all of the following EXCEPT:
A. It inhibits the uptake of norepinephrine into vesicles and MAO
B. It decreases cardiac output, peripheral resistance and inhibits pressor reflexes
C. It may cause a transient sympathomimetic effect
D. It depletes stores of catecholamines and serotonin in the brain

10. Indicate the neuromuscular blocker, whose breakdown product readily crosses the blood-brain barrier and may cause seizures:
A. Pancuronium
B. Succinylcholine
C. Tubocurarine
D. Atracurium

11. Indication for calcium administration is:
A. Failure of formation of vitamin D in skin
B. Malabsorption of vitamin D from intestine
C. Hypercalcemia of malignancy
D. Vitamin D deficiency

12. The drug that can be given intravenously but not into the infusion bottle :
A. Ampicillin
B. Penicillin G sodium
C. Gentamicin
D. Frusemide

13. Which of the following drugs would most likely need a loading dose to help reach therapeutic levels?
A. Acetaminophen, t(1/2) = 2 h
B. Aspirin, t(1/2) = 15 m
C. Tetracycline, t(1/2) = 11 h
D. Digitoxin, t(1/2) = 161 h

14. Tick the drug, inhibiting oxidative phosphorylation in some species of helminthes:
A. Niclosamide
B. Piperazine
C. Praziquantel
D. Mebendazole

15. Which of the following drugs is useful for the treatment of advanced prostate cancer?
A. Ganirelix
B. Cetrorelix
C. Abarelix
D. Goserelin

16. All of the following drugs demonstrate a fungicidal effect, EXCEPT:
A. Terbinafin
B. Amfotericin B
C. Ketoconazole
D. Myconazol

17. Tick the luminal amebecide drug:
A. Metronidazole
B. Emetine
C. Doxycycline
D. Diloxanide

18. Immunosupressive effect of glucocorticoids is caused by
A. Reducing concentration of lymphocytes (T and B cells) and inhibiting function of tissue macrophages and other antigen-presenting cells
B. Suppression of cyclooxygenase II expression that results in reducing amount of an enzyme available to produce prostoglandins
C. Activation of phospholipase A2 and reducing prostaglandin and leukotriene synthesis
D. All of these

19. Patients who experience migraines
A. can be treated with a combination of migraine medications.
B. should not be treated with a combination of migraine medications.
C. should be treated with amphetamines.
D. should be treated with Prozac

20. Which of the following symptoms are possible side effects of an antibiotic?
A. Rash
B. Fever
C. Hives and itching
D. All of these

Dr K Chaudhry 5 Alpha Inmternational City, Fatehabad 125050 M: 9810570740, 9810571993facebook.com/doctorkc