A fresh set of 20 random questions is generated every time you open this page and every time you refresh it.For each of the following multiple choice questions, choose the most appropriate answer :
1. The anticoagulant induced hypoprothrombinaemia is most rapidly reversed by :
A. Dextran
B. Haemaccel
C. Normal Saline
D. Fresh blood or plasma
2. How many doses of nitroglycerin should a patient take for an angina attack?
A. 3
B. 5
C. 1
D. None
3. Indicate an alfa receptor antagonist, which is an efficacious drug in the treatment of mild to moderate systemic hypertension:
A. Phentolamine
B. Tolazoline
C. Ergotamine
D. Prazosin
4. Tick the drug, a benzimidazole derivative:
A. Praziquantel
B. Mebendazole
C. Suramin
D. Pyrantel
5. Which of the following locations can accumulate lipid-soluble drugs, has little or no receptors, and can hold distributed drugs like barbiturates?
A. Liver
B. Kidney
C. Brain
D. Fat
6. The combination of disulfiram and ethanol leads to accumulation of:
A. Formaldehyde
B. Acetate
C. Formic acid
D. Acetaldehyde
7. Lithium potentiates the action of non-depolarizing muscle relaxants. How many days before administration of the muscle relaxant should lithium be stopped?
A. 1 day
B. 2 days
C. 3 days
D. 4 days
8. What is the main action of GABA derivatives in disorders of brain circulation?
A. Decrease of vessel permeability
B. Stimulation of the metabolic processes in neurons
C. Brain vessel constriction
D. Intracranial pressure increase
9. Which of the following is NOT a phase II substrate?
A. Glucuronic acid
B. Sulfuric acid
C. Acetic acid
D. Alcohol
10. Subtype-selective alfa1 receptor antagonists such as tamsulosin, terazosin, alfusosin are efficacious in:
A. Hyperthyroidism
B. Cardiac arrhythmias
C. Benign prostatic hyperplasia (BPH)
D. Asthma
11. A decrease in drug-protein binding will lead to which of the following?
A. Decrease in the unbound drug concentration
B. Increase in free drug
C. Increase in rate of drug elimination
D. Decrease in volume of distribution
12. Drugs come from
A. animals.
B. humans.
C. plants.
D. All of these
13. Which of the following nitrates and nitrite drugs is a short-acting drug?
A. Nitroglycerin, 2% ointment (Nitrol)
B. Nitroglycerin, oral sustained-release (Nitrong)
C. Amyl nitrite, inhalant (Aspirols, Vaporole)
D. Sustac
14. Fetal Hydantoin Syndrome is cause by
A. Phenytoin
B. Alcohol
C. Tetracycline
D. Sodium valproate
15. The drug is a potassium-sparing diuretic that blocks Na+ channels in the collecting tubules:
A. Acetazolamide (Diamox)
B. Amiloride (Midamor)
C. Furosemide (Lasix)
D. Hydrochlorothiazide (HydroDiuril)
16. The mechanism of carbidopa?s action is:
A. Stimulating the synthesis, release, or reuptake of dopamine
B. Inhibition of dopa decarboxilase
C. Stimulating dopamine receptors
D. Selective inhibition of catecol-O-methyltransferase
17. Which category of histamine H1 antagonists is noted for the best antiemetic action?
A. Alkylamines (propylamines); i.e. Brompheniramine
B. Ethanolamines (aminoalkyl ethers); i.e. Doxylamine
C. Piperazines; i.e. Hydroxyzine, Cyclizine
D. Ethylenediamines; i.e. Suprastine
18. All of the following antibiotics are macrolides, EXCEPT:
A. Erythromycin
B. Clarithromycin
C. Lincomycin
D. Roxythromycin
19. Correct statements about alendronate include all of the following, EXCEPT:
A. Can be irritable to the esophagus if not washed promptly to the stomach
B. 1st generation biphosphonate
C. Reduces osteoclast activity without significantly affecting osteoblasts; useful in the treatment of Paget's disease
D. More potent than EHDP; has a wider therapeutic window
20. All of the following are common adverse effects of calcium channel blockers EXCEPT:
A. Skeletal muscle weakness
B. Dizziness
C. Headache
D. Flushing
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