A fresh set of 20 random questions is generated every time you open this page and every time you refresh it.For each of the following multiple choice questions, choose the most appropriate answer :
1. Compared with epinephrine, norepinephrine produces all of the following effects EXCEPT:
A. Similar effects on beta1 receptors in the heart and similar potency at an alfa receptor
B. Decrease the mean pressure below normal before returning to the control value
C. Significant tissue necrosis if injected subcutaneously
D. Increase both diastolic and systolic blood pressure
2. Pick out the drug which increases cardiac output:
A. Noradrenalin
B. Methyldopa
C. Phenylephrine
D. Angiotensinamide
3. Pick out the sympatholythic drug:
A. Labetalol
B. Prazosin
C. Guanethidine
D. Clonidine
4. What cells produce hydrochloric acid in the stomach?
A. Gastrin-producing cells
B. Parietal cells
C. Mucus-producing cells
D. None of these
5. Which of the following reversible cholinesterase inhibitors is used for Alzheimer disease?
A. Neostigmine
B. Physostigmine
C. Endrophonium
D. Donepezil
6. Indicate the antidepressant agent, which is a phenyltolylpropylamine derivative:
A. Paroxetine
B. Maprotiline
C. Fluoxetine
D. Amitriptyline
7. Which of the following drug targets involves inhibitors, false substrates, and a pro-drug type?
A. Receptors
B. Ion channels
C. Enzymes
D. Carriers
8. Indicate the group of drugs influencing the cerebral flow:
A. Ca-channel blockers
B. Derivatives of GABA
C. Derivatives of Vinca minor plant
D. All the above
9. Indicate the local anesthetic, which is mainly used for regional nerve block anesthesia:
A. Dibucaine
B. Bupivacaine
C. Tetracaine
D. Cocaine
10. These histamine H1 antagonists are recognized for as second-generation antihistamines, EXCEPT:
A. Astemizole
B. Loratadine (Claritin)
C. Cetirizine (Zyrtec)
D. Suprastine
11. The rate of secretion of thyrotropin is controlled by:
A. The amount of iodine in the thyroid gland
B. The amount of thyroid hormones in the thyroid gland
C. The concentration of thyroid hormones in blood
D. The concentration of catecholamines in blood
12. Pharmacokinetics is:
A. The study of biological and therapeutic effects of drugs
B. The study of absorption, distribution, metabolism and excretion of drugs
C. The study of mechanisms of drug action
D. The study of methods of new drug development
13. Monoamine Oxydase A:
A. Is responsible for norepinephrine, serotonin, and tyramine metabolism
B. Is more selective for dopamine
C. Metabolizes norepinephrine and dopamine
D. Deaminates dopamine and serotonin
14. Indication for pamidronate administration is:
A. Failure of vitamin D formation in skin
B. Hypoparathyroidism
C. Elevated skeletal turnover
D. Hypercalcemia
15. Mechanisms of bacterial resistance to anti-microbial agents are the following, EXCEPT:
A. Active transport out of a microorganism or/and hydrolysis of an agent via enzymes produced by a microorganism
B. Enlarged uptake of the drug by a microorganism
C. Modification of a drug’s target
D. Reduced uptake by a microorganism
16. Nephrotoxicity is seen with ? :
A. C.Mycophenolate mofetil
B. D.Tacrolimus
C. Leflunomide
D. Azathioprine
17. What does the term “potentiation” mean?
A. Cumulative ability of a drug
B. Hypersensitivity to a drug
C. Fast tolerance developing
D. Intensive increase of drug effects due to their combination
18. Which of the following adverse effects is associated with lithium treatment?
A. Cardiovascular anomalies in the newborn
B. Thyroid enlargement
C. Nephrogenic diabetes insipidus
D. All of these
19. Drug causing acquired Nasolacrimal duct obstruction
A. Timolol
B. Pilocarpine
C. Dorzolamide
D. Brimonidine
20. Levodopa should not be given to patients taking:
A. Bromocriptine
B. Monoamine oxydase A inhibitors
C. Carbidopa
D. Nonselective beta-adrenergic antagonists
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