A fresh set of 20 random questions is generated every time you open this page and every time you refresh it.For each of the following multiple choice questions, choose the most appropriate answer :
1. Indicated the inhaled anesthetic, which decreases the ventilatory response to hypoxia:
A. Sevoflurane
B. Nitrous oxide
C. Desflurane
D. Halothane
2. Mental confusion and hallucinations, peripheral atropine-like toxicity (e.g. Cycloplegia, tachycardia, urinary retention, and constipation) are possible adverse effects of:
A. Sinemet
B. Benztropine
C. Tolkapone
D. Bromocriptine
3. Beta-blocking drugs-induced chronically lower blood pressure may be associated with theirs effects on:
A. The heart
B. The blood vessels
C. The renin-angiotensin system
D. All of these
4. The principal mechanism of action of antidepressant agents is:
A. Stabilization of dopamine and beta-adrenergic receptors
B. Inhibition of the storage of serotonin and epinephrine in the vesicles of presynaptic nerve endings
C. Blocking epinephrine or serotonin reuptake pumps
D. Stimulation of alfa2-norepinephrine receptors
5. Which of the following antidepressants is used for treatment of eating disorders, especially buliemia?
A. Amitriptyline
B. Fluoxetine
C. Imipramine
D. Tranylcypromine
6. In an area where goitre is endemic, which of the following drugs is used?
A. Iodide 1 part in 100000
B. Propylthiouracil 200 mg daily
C. Methimazole 40 mg daily
D. Any of the above can be used.
7. Which of the following is NOT a primary effect of stimulating muscarinic M receptors?
A. Tachycardia, increased conduction velocity
B. Increased GI tract tone and secretions
C. Diaphoresis from sweat glands
D. Penile erection
8. All of the following statements regarding cardiac glycoside-induced ventricular tachyarrhythmias are true EXCEPT:
A. Lidocaine is a drug of choice in treatment
B. Digibind should be used in life-threatening cases
C. They occur more frequently in patients with hyperkalemia than in those with hypokalemia
D. They are more likely to occur in patients with a severely damaged heart
9. What is a result of conjugation of isoniazid via N-acetylation?
A. Detoxification of liver
B. Detoxification of kidneys
C. Detoxification of urine
D. Hepatotoxicity
10. Which of the following agents is an alfa2-selective agonist with ability to promote constriction of the nasal mucosa?
A. Xylometazoline
B. Phenylephrine
C. Methoxamine
D. Epinephrine
11. Compared with atropine, scopolamine has all of the following properties EXCEPT:
A. More marked central effect
B. Less potent in decreasing bronchial, salivary and sweat gland secretion
C. More potent in producing mydriasis and cycloplegia
D. Lower effects on the heart, bronchial muscle and intestines
12. Metoprolol and atenolol:
A. Are members of the beta1-selective group
B. Are nonselective beta antagonists
C. Have intrinsic sympathomimetic activity
D. Have an anesthetic action
13. Indicate the alfa2-selective agonist:
A. Xylometazoline
B. Epinephrine
C. Dobutamine
D. Methoxamine
14. Indication for administration of histamine H1 antagonists is:
A. Prevention or treatment of the symptoms of allergic reactions (rhinitis, urticaria)
B. Motion sickness and vestibular disturbances
C. Nausea and vomiting in pregnancy (“morning sickness”)
D. All of these
15. The mechanism of action of antiseizure drugs is:
A. Enhancement of GABAergic (inhibitory) transmission
B. Diminution of excitatory (usually glutamatergic) transmission
C. Modification of ionic conductance
D. All of these
16. Parkinson?s syndrome, acute dystonic reactions, tardive dyskinesia, antimuscarinic actions, orthostatic hypotension, galactorrhea are possible adverse effects of:
A. Haloperidol
B. Clozapine
C. Chlorpromazine
D. Risperidone
17. Which of the following drugs is useful for the treatment of advanced prostate cancer?
A. Ganirelix
B. Cetrorelix
C. Abarelix
D. Goserelin
18. Indicate the drugs of choice for reversing the withdrawal syndrome:
A. Benzodiazepines
B. Neuroleptics
C. Antidepressants
D. All of these
19. Pharmacokinetics is:
A. The study of biological and therapeutic effects of drugs
B. The study of absorption, distribution, metabolism and excretion of drugs
C. The study of mechanisms of drug action
D. The study of methods of new drug development
20. Which of the following disadvantages does not limit using benzodiazepines as antianxiety agents?
A. Tendency to develop psychologic dependence
B. A high risk of drug interactions based on liver enzyme induction
C. a)Synergic CNS depression with concomitant use of other drugs
D. b)The formation of active metabolites
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