Test Your Knowledge - Free MCQ PRACTICE
pharmacology
by Dr K Chaudhry
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A fresh set of 20 random questions is generated every time you open this page and every time you refresh it.
For each of the following multiple choice questions, choose the most appropriate answer :

1. The drug acts at the proximal tubule:
A. Loop diuretics
B. Thiazide diuretics
C. Potassium-sparing diuretics
D. Carbonic anhydrase inhibitors

2. Indicate the benzodiazepine, which has the shortest elimination half-life:
A. Quazepam
B. Triazolam
C. Diazepam
D. Clorazepate

3. The mechanism of fluoxetine action includes:
A. Selective inhibition of serotonine uptake in the CNS
B. Little effect on central norepinephrine or dopamine function
C. Minimal binding to cholinergic, histaminic, and alfa-adrenergic receptors
D. All of these

4. Which of the following glucocorticoids is an intermediate-acting drug?
A. Cortisone
B. Triamcinolone
C. Butamethasone
D. All of these

5. Which of the following inhaled anesthetics decreases metheonine synthase activity and causes megaloblastic anemia?
A. Desflurane
B. Halothane
C. Nitrous oxide
D. Soveflurane

6. These drugs may be used in the treatment of recurrent calcium nephrolithiasis:
A. Osmotic diuretics
B. Loop diuretics
C. Thiazide diuretics
D. Potassium-sparing diuretics

7. For increasing blood pressure in case of low cardiac output the following agents must be used:
A. Ganglioblockers
B. Vasoconstrictors
C. Positive inotropic drugs
D. Diuretics

8. This drug is a desintoxicative plasma substitute:
A. Polyglucinum
B. Haemodesum
C. Sodium chloridum isotonic for injections
D. "Disolum", "Trisolum"

9. Indicate the usual cause of death due to overdose of hypnotics:
A. Depression of the medullar respiratory center
B. Hypothermia
C. Cerebral edema
D. Status epilepticus

10. Correct the statements concerning ketorolac include all of the following EXCEPT:
A. It inhibits COX
B. It is as effective as morphine for a short-term relief from moderate to severe pain
C. It has a high potential for physical dependence and abuse
D. It does not produce respiratory depression

11. Which of the following sympathomimetics acts indirectly?
A. Epinephrine
B. Norepinephrine
C. Ephedrine
D. Methoxamine

12. Antibiotic inhibiting bacterial RNA synthesis is:
A. Erythromycin
B. Rifampin
C. Chloramphenicol
D. Imipinem

13. Which of the following non-narcotic agents is salicylic acid derivative?
A. Phenylbutazone
B. Ketamine
C. Aspirin
D. Tramadol

14. Antibiotic associated with Colitis
A. Neomycin
B. Chloramphenicol
C. Clindamycin
D. Vancomycin

15. The uptake of glucose by calls is an example of :
A. Simple diffusion
B. Filtration
C. Active transport
D. Faciliated diffusion

16. Non-narcotic agents cause:
A. Respiratory depression
B. Antipyretic effect
C. Euphoria
D. Physical dependence

17. Which of the following drugs is a leucotreine D4 receptor (LTD4) blocker?
A. Ibuprofen
B. Zileuton (Zyflo)
C. Zafirleukast (Accolate)
D. Diclofenac

18. Therapeutic index (TI) is:
A. A ratio used to evaluate the safety and usefulness of a drug for indication
B. A ratio used to evaluate the effectiveness of a drug
C. A ratio used to evaluate the bioavailability of a drug
D. A ratio used to evaluate the elimination of a drug

19. Which of the following agents is a nonselective beta receptor agonist?
A. Norepinephrine
B. Terbutaline
C. Isoproterenol
D. Dobutamine

20. Aspirin is a weak organic acid with a pKa of 3.5. What percentage of a given dose will be in the lipid-soluble form at a stomach pH of 1.5?
A. About 10%
B. About 50%
C. About 90%
D. About 99%

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