A fresh set of 20 random questions is generated every time you open this page and every time you refresh it.For each of the following multiple choice questions, choose the most appropriate answer :
1. Which of the following is considered the brand name?
A. Propranolol
B. Inderal
C. Adrenergic ß-blocker
D. Mepyramine
2. Indicate the barbituric acid derivative, which has 4-5 days elimination half-life:
A. Secobarbital
B. Thiopental
C. Phenobarbital
D. Amobarbital
3. Tick narcotic analgesic, which is a phenylpiperidine derivative:
A. Codeine
B. Dezocine
C. Fentanyl
D. Buprenorphine
4. For therapeutic application local anesthetics are usually made available as salts for the reasons of:
A. Less toxicity and higher potency
B. Higher stability and greater lipid solubility
C. Less local tissue damage and more potency
D. More stability and greater water solubility
5. Which of the following drugs is a 5-lipoxygenase (5-LOG) inhibitor?
A. Ibuprofen
B. Zileuton (Zyflo)
C. Metamizole (Analgin)
D. Diclofenac
6. Ritonovir inhibits all except?
A. Amiodarone
B. Cisapride
C. Phenytoin
D. Midazolam
7. HIV is transmitted via
A. injection of infected blood or blood products.
B. sexual contact.
C. maternal–fetal transmission.
D. All of these
8. Propantheline is a :
A. Sympathomimetic drug
B. Sympatholytic drug
C. Parasympathomimetic drug
D. Parasympatholytic drug
9. Indicate the drugs which are Ca-channel blockers influencing the brain blood flow:
A. Aminalon, Picamilon
B. Nimodipine, Cinnarizine
C. Heparin, Warfarin
D. Vinpocetine, Nicergoline
10. Dopamine in high doses influences mainly the:
A. Alfa-adrenoreceptors (leads to peripheral vasoconstriction)
B. Dopamine’s receptors (leads to vasodilation of renal and mesenterial vessels)
C. Beta-1 adrenoreceptors (leads to enhancing of cardiac output)
D. All of these
11. Which of the following analgesics is a phenanthrene derivative?
A. Fentanyl
B. Morphine
C. Methadone
D. Pentazocine
12. These histamine H1 antagonists are recognized for as second-generation antihistamines, EXCEPT:
A. Astemizole
B. Loratadine (Claritin)
C. Cetirizine (Zyrtec)
D. Suprastine
13. Currently used oral hypoglycemic biguanides include the following, EXCEPT:
A. Repaglinide (Prandin)
B. Metformin
C. Phenformine
D. Glipizide
14. What type of study for an IND involves comparison with a placebo and another previously tested drug?
A. Single-blind study
B. Double-blind study
C. Placebo (negative-control)
D. Positive-control
15. If a drug is 80% bound to blood elements or plasma proteins, what part is considered the free form?
A. 20%
B. 40%
C. 50%
D. 80%
16. Pain occurring from skeletal muscles, fascia, ligaments, vessels, and joints is called
A. neuropathic pain.
B. visceral pain.
C. chronic pain.
D. None of these
17. Indicate the agent, which effectively antagonizes the neuromuscular blockade caused by nondepolarizing drugs:
A. Atropine
B. Neostigmine
C. Acetylcholine
D. Pralidoxime
18. Which of the following antipsychotic agents is used in combination with an opioid drug fentanyl in neuroleptanalgesia?
A. Haloperidol
B. Droperidol
C. Chlorpromazine
D. Clozapine
19. What does “pharmacokinetics” include?
A. Pharmacological effects of drugs
B. Unwanted effects of drugs
C. Chemical structure of a medicinal agent
D. Distribution of drugs in the organism
20. Half life (t ½) doesn’t depend on:
A. Biotransformation
B. Time of drug absorption
C. Concentration of a drug in plasma
D. Rate of drug elimination
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