A fresh set of 20 random questions is generated every time you open this page and every time you refresh it.For each of the following multiple choice questions, choose the most appropriate answer :
1. Exudation is a result of damage to :
A. Arteriolar endothelium
B. Capillary enclothelium
C. Cell wall of interstitial cells
D. Nerve endings
2. Free radicals
A. are not a byproduct of metabolism.
B. can only form in the presence of oxygen.
C. may arise by absorption of radiant energy.
D. are removed with the aid of Vitamin A derivatives
3. A substance that is not known to accumulate intracellularly is
A. melanin.
B. haemosiderin.
C. tattoo ink.
D. pus
4. A tumour affecting only one segment of a blood vessel to the skin or mucous membrane of the nose is most likely a :
A. Sclerosing haemangioma
B. Capillary haemangioma
C. Cavernous haemangioma
D. Haemangio-endothelioma
5. Leukocyte adhesion with transmigration involves all of the following EXCEPT
A. migration of leukocytes as a result of stasis of blood flow in the microvasculature.
B. interaction of integrins with immunoglobulin found on endothelial cells.
C. the selectins found only on endothelial cells.
D. ICAM-1 and VCAM-1 adhesive molecules on the endothelial cells
6. The most important cause of oedema in nephrotic syndrome is :
A. Hypoproteinaemia
B. Increased capillary permeability
C. Increased hydrostatic pressure of blood
D. Lymphatic obstruction
7. All of the following are features of apoptosis, except
A. Cellular swelling
B. nuclear compaction
C. intact cell membrane
D. Cytoplasmic eosinophlia
8. Dystrophic calcification :
A. occurs in dead or dying tissues
B. occurs in hypertrophied tissue
C. occurs in hypercalcaemia
D. occurs in hypervitaminosis D
9. Characteristic of primary syphilis :
A. Hunterian chancre
B. Incubation period 1-10 days
C. Positive Wassermann reaction
D. Exudate contains chiefly polymorphs
10. Cystic fibrosis is inherited as an autosomal recessive condition. A normal couple has one daughter affected with the disease. They are now planning to have another child. What is the cause of her sibling being affected by the disease?
A. 0
B. 1/2
C. 1/4
D. 3/4
11. A synonym for amyloidosis is :
A. alpha-fibrillosis
B. beta-fibrillosis
C. gamma-fibrillosis
D. Cysteinosis
12. Histopathologically, rosettes are not seen in
A. Retinoblastoma
B. Neurocysticercosis
C. PNET
D. Medulloblastoma
13. Congenital heart disease most likely to cause cyanosis is :
A. Patent foramen ovale
B. Patent ductus arteriosus
C. Atrial septal defect
D. Ventricular septal defect
14. The spreading factor, hyaluronidase is found in :
A. Clostridium welchii
B. Testicular tissue
C. Malignant tumours
D. All of these
15. A young female is most likely to develop :
A. Polyarteritis nodosa
B. Temporal arteritis
C. Aortic arch syndrome
D. Wegener's granulomatosis
16. Endothelial derived antithrombotic factors include all of the following, except:
A. PGI2
B. NO
C. protein S
D. plasminogen
17. Brown induration is a type of chronic venous congestion occuring in :
A. Liver
B. Heart
C. Lung
D. Kidney
18. Severe haemolytic transfusion reactions commonly occur when
A. the transfused blood contains antibodies against the recipient cells.
B. the recipient has a high titre of antibodies against the donor cells.
C. Group A blood is transfused into Group AB recipients.
D. Group O blood is transfused into Group A recipients
19. Hypercoagulation in nephritic syndrome is caused by
A. Loss of Antithrombin III
B. Decreased fibrinogen
C. Decreased metabolism of vitamin K
D. Increase in protein C
20. Breast cancer is predisposed by :
A. Increase in estrogen
B. Decrease in estrogen
C. Increase in androgen
D. Decrease in androgen
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