Vaccine

There is currently no vaccine to protect against COVID-19.

A number of vaccines are in pipeline – First two in Pase I of Clinical evaluation; others in Preclinical stage :-

 

Vaccine

Developer

1

Adenovirus Type 5 Vector

CanSino Biological Inc. and Beijing Institute of Biotechnology

2

LNPencapsulated mRNA

Moderna/NIAID

3

DNA plasmid vaccine Electroporation device

Inovio Pharmaceuticals

4

DNA

Takis/Applied DNA Sciences/Evvivax

5

DNA plasmid vaccine

Zydus Cadila

6

Formaldehydeinactivated + alum

Sinovac

7

Deoptimized live attanuated vaccines

Codagenix/Serum Institute of India

8

MVA encoded VLP

GeoVax/BravoVax

9

Ad26 (alone or with MVA boost)

Janssen Pharmaceutical Companies

10

ChAdOx1

University of Oxford

11

Adenovirusbased NasoVAX expressing SARS2-CoV spike protein

Altimmune

12

Ad5 S (GREVAX™ platform)

Greffex

13

Oral Vaccine platform

Vaxart

14

Drosophila S2 insect cell expression system VLPs

ExpreS2ion

15

S protein

WRAIR/USAMRIID

16

S-Trimer

Clover Biopharmaceuticals Inc./GSK

17

Peptide

Vaxil Bio

18

S protein

AJ Vaccines

19

Ii-Key peptide

Generex/EpiVax

20

S protein

EpiVax/Univ. of Georgia

21

S protein (baculovirus production)

Sanofi Pasteur

22

Full length S trimers/ nanoparticle + Matrix M

Novavax

23

gp-96 backbone

Heat Biologics/Univ. Of Miami

24

Molecular clamp stabilized Spike protein

University of Queensland/GSK

25

S1 or RBD protein

Baylor College of Medicine

26

Subunit protein, plant produced

iBio/CC-Pharming

27

Subunit

VIDO-InterVac, University of Saskatchewan

28

Adjuvanted microsphere peptide

University of Saskatchewan

29

Measles Vector

Zydus Cadila

30

Measles Vector

Institute Pasteur/Themis/Univ. of Pittsburg Center for Vaccine Research

31

Horsepox vector expressing S protein

Tonix Pharma/Southern Research

32

LNPencapsulated mRNA cocktail encoding VLP

Fudan University/ Shanghai JiaoTong University/RNACure Biopharma

33

LNPencapsulated mRNA encoding RBD

Fudan University/ Shanghai JiaoTong University/RNACure Biopharma

34

mRNA

China CDC/Tongji University/Stermina

35

mRNA

Arcturus/Duke-NUS

36

mRNA

BioNTech/Fosun Pharma/Pfizer

37

mRNA

Imperial College London

38

mRNA

Curevac

39

Plant-derived VLP

Medicago Inc.

40

Unknown

University of Hong Kong

41

Unknown

ImmunoPrecise

42

Unknown

MIGAL Galilee Research Institute

43

Unknown

Doherty Institute

44

Unknown

Tulane University

 


 

 


 Contents

 

Chapter

 

Abstract

01

Introduction

02

Evolution

03

Corona pandemic data in India

04

Headline facts

05

Corona virus

06

Corona virus Pandemics

07

Disease\s caused

08

Spread

09

Symptoms

10

Complications

11

Prevention

12

Vaccine

13

Treatment

14

Immunity boosters

 

Bibliography