There is currently no vaccine to protect against COVID-19.
A number of vaccines are in pipeline – First two in Pase I of Clinical evaluation; others in Preclinical stage :-
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Vaccine |
Developer |
|
1 |
Adenovirus Type 5 Vector |
CanSino Biological Inc. and Beijing Institute of Biotechnology |
|
2 |
LNPencapsulated mRNA |
Moderna/NIAID |
|
3 |
DNA plasmid vaccine Electroporation device |
Inovio Pharmaceuticals |
|
4 |
DNA |
Takis/Applied DNA Sciences/Evvivax |
|
5 |
DNA plasmid vaccine |
Zydus Cadila |
|
6 |
Formaldehydeinactivated + alum |
Sinovac |
|
7 |
Deoptimized live attanuated vaccines |
Codagenix/Serum Institute of India |
|
8 |
MVA encoded VLP |
GeoVax/BravoVax |
|
9 |
Ad26 (alone or with MVA boost) |
Janssen Pharmaceutical Companies |
|
10 |
ChAdOx1 |
University of Oxford |
|
11 |
Adenovirusbased NasoVAX expressing SARS2-CoV spike protein |
Altimmune |
|
12 |
Ad5 S (GREVAX™ platform) |
Greffex |
|
13 |
Oral Vaccine platform |
Vaxart |
|
14 |
Drosophila S2 insect cell expression system VLPs |
ExpreS2ion |
|
15 |
S protein |
WRAIR/USAMRIID |
|
16 |
S-Trimer |
Clover Biopharmaceuticals Inc./GSK |
|
17 |
Peptide |
Vaxil Bio |
|
18 |
S protein |
AJ Vaccines |
|
19 |
Ii-Key peptide |
Generex/EpiVax |
|
20 |
S protein |
EpiVax/Univ. of Georgia |
|
21 |
S protein (baculovirus production) |
Sanofi Pasteur |
|
22 |
Full length S trimers/ nanoparticle + Matrix M |
Novavax |
|
23 |
gp-96 backbone |
Heat Biologics/Univ. Of Miami |
|
24 |
Molecular clamp stabilized Spike protein |
University of Queensland/GSK |
|
25 |
S1 or RBD protein |
Baylor College of Medicine |
|
26 |
Subunit protein, plant produced |
iBio/CC-Pharming |
|
27 |
Subunit |
VIDO-InterVac, University of Saskatchewan |
|
28 |
Adjuvanted microsphere peptide |
University of Saskatchewan |
|
29 |
Measles Vector |
Zydus Cadila |
|
30 |
Measles Vector |
Institute Pasteur/Themis/Univ. of Pittsburg Center for Vaccine Research |
|
31 |
Horsepox vector expressing S protein |
Tonix Pharma/Southern Research |
|
32 |
LNPencapsulated mRNA cocktail encoding VLP |
Fudan University/ Shanghai JiaoTong University/RNACure Biopharma |
|
33 |
LNPencapsulated mRNA encoding RBD |
Fudan University/ Shanghai JiaoTong University/RNACure Biopharma |
|
34 |
mRNA |
China CDC/Tongji University/Stermina |
|
35 |
mRNA |
Arcturus/Duke-NUS |
|
36 |
mRNA |
BioNTech/Fosun Pharma/Pfizer |
|
37 |
mRNA |
Imperial College London |
|
38 |
mRNA |
Curevac |
|
39 |
Plant-derived VLP |
Medicago Inc. |
|
40 |
Unknown |
University of Hong Kong |
|
41 |
Unknown |
ImmunoPrecise |
|
42 |
Unknown |
MIGAL Galilee Research Institute |
|
43 |
Unknown |
Doherty Institute |
|
44 |
Unknown |
Tulane University |
Contents
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Chapter |
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01 |
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02 |
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03 |
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04 |
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05 |
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06 |
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07 |
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08 |
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09 |
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11 |
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12 |
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13 |
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14 |
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Bibliography |